| 基因名 | 突变 |
|---|---|
| TOP2A(NM_001067,topoisomerase (DNA) II alpha 170kDa,1531aa) | g.17:38552666C>G,c.3589G>C,p.G1197R |
| TOP2A(NM_001067,topoisomerase (DNA) II alpha 170kDa,1531aa) | g.17:38552665C>T,c.3590G>A,p.G1197E |
| TOP2A(NM_001067,topoisomerase (DNA) II alpha 170kDa,1531aa) | g.17:38552665C>G,c.3590G>C,p.G1197A |
| TOP2A(NM_001067,topoisomerase (DNA) II alpha 170kDa,1531aa) | g.17:38548888C>T,c.3913G>A,p.E1305K |
| TOP2A(NM_001067,topoisomerase (DNA) II alpha 170kDa,1531aa) | g.17:38548867G>A,c.3934C>T,p.P1312S |
| TOP2A(NM_001067,topoisomerase (DNA) II alpha 170kDa,1531aa) | g.17:38547868C>T,c.4157G>A,p.G1386D |
| TOP2A(NM_001067,topoisomerase (DNA) II alpha 170kDa,1531aa) | g.17:38545824C>A,c.4543G>T,p.A1515S |
| TOP1(NM_003286,topoisomerase (DNA) I,765aa) | g.20:39704896C>T,c.241C>T,p.H81Y |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144411548C>T,c.38G>A,p.R13Q |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144411525G>A,c.61C>T,p.R21X |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144408508C>T,c.73G>A,p.A25T |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144408480C>T,c.101G>A,p.S34N |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144407675T>C,c.218A>G,p.Q73R |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144406773G>A,c.404C>T,p.A135V |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144406705C>T,c.472G>A,p.V158I |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144406174C>T,c.661G>A,p.D221N |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144403532T>C,c.691A>G,p.K231E |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144403526C>T,c.697G>A,p.D233N |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144403523C>T,c.700G>A,p.G234S |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144403475C>T,c.748G>A,p.V250I |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144403466G>A,c.757C>T,p.H253Y |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144399893C>T,c.1036G>A,p.A346T |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144398257C>G,c.1076G>C,p.R359P |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144398191G>A,c.1142C>T,p.S381L |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144392368G>A,c.1279C>T,p.R427W |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144391706G>A,c.1417C>T,p.R473W |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144391705C>T,c.1418G>A,p.R473Q |
| TOP1MT(NM_001258446,topoisomerase (DNA) I, mitochondrial,503aa) | g.8:144391664G>A,c.1459C>T,p.R487W |